PATIENT ELIGIBILITY

Offer the Cologuard® test to every eligible patient aged 45 and older at average risk for colorectal cancer (CRC)1,2

For over 10 years, over 380,000 healthcare providers have trusted the Cologuard test to screen over 15 million patients.3,4*

Chart showing which patients are eligible and not eligible to screen for CRC with a Cologuard test.

The Cologuard-first screening approach

With this approach, you can reserve colonoscopy for the patients who need it the most.

Flow chart evaluating patient risk for CRC to demonstrate the Cologuard®-first screening approach.
Cologuard box.

Which patients receive the Cologuard Plus™ test vs the Cologuard test?

Eligibility criteria for both tests are the same. Exact Sciences will determine which test your patients receive based on which test their insurance covers.

Learn More

This primary care physician chose the Cologuard test to screen himself for CRC

Dr Fenton is an average-risk patient with no family history of CRC. Watch how he caught CRC early.

Cologuard performance

Explore the sensitivity and specificity of the Cologuard test

View The Data
  • * Data as of January 31, 2025.3
  • † Such as hereditary nonpolyposis CRC syndrome (or Lynch syndrome), Peutz-Jeghers syndrome, MYH-associated polyposis, Gardner’s syndrome, Turcot’s (or Crail’s) syndrome, Cowden’s syndrome, juvenile polyposis, Cronkhite-Canada syndrome, neurofibromatosis, or familial hyperplastic polyposis.1,2
  • ‡For patients with traditional Medicare, a colonoscopy after a positive Cologuard result is still a screening colonoscopy based on updated Centers for Medicare & Medicaid Services regulations, effective January 1, 2023. Medicare does not apply cost sharing to screening colonoscopy. This update does not apply to commercial plans with exempted status.5,6

FAP=familial adenomatous polyposis; IBD=inflammatory bowel disease; UC=ulcerative colitis.