HCP RESOURCES
Cologuard® resources for HCPs
You can download and share resources with your peers directly from this page, or you can contact a rep to request materials. If you have any questions or need further assistance, please call our Customer Care Center at 1-844-870-8870 or chat online. You may also find answers to any questions on the FAQs page.
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Clinical information
Study Data for the Cologuard Plus™ Test as Published in The New England Journal of Medicine
Study published in 2024 detailing the sensitivity, specificity, and other clinical data for the Cologuard Plus test.
Imperiale TF, Porter K, Zella J, et al. Next-generation multitarget stool DNA test for colorectal cancer screening. 2024.
Please note that this test is not yet available.
Cologuard Clinician Brochure
Complete prescribing information for the Cologuard test.
Pivotal Study Data for the Cologuard Test as Published in The New England Journal of Medicine
Pivotal study published in 2014 detailing the sensitivity, specificity, and other clinical data for the Cologuard test.
Imperiale TF, Ransohoff DF, Itzkowitz SH, et al. Multitarget stool DNA testing for colorectal-cancer screening. 2014.
Retrospective Study Data on Cologuard Adherence as Published in The World Journal of Gastroenterology
Retrospective study published in 2017 detailing Cologuard adherence among eligible patients who were previously nonadherent to CRC screening.
Prince M, Lester L, Chiniwala R, Berger B. Multitarget stool DNA tests increases colorectal cancer screening among previously noncompliant Medicare patients. 2017.
Study Data on Shared Decision-Making as Published in The Annals of Family Medicine
Study published in 2022 detailing the impact of shared decision-making on CRC screening acceptance.
Verma P, Cohen K, Berke EM. The effect of a shared decision-making process on acceptance of colorectal cancer screening. 2022.
Study Data on Follow-up Colonoscopy as Published in Gastrointestinal Endoscopy
Study published in 2017 detailing the impact that a positive stool-based CRC screening test can have on follow-up colonoscopy.
Johnson DH, Kisiel JB, Burger KN, et al. Multitarget stool DNA test: clinical performance and impact on yield and quality of colonoscopy for colorectal cancer screening, 2017.
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Operational information
Order a Cologuard Test Through EpicCare® LinkTM EMR Summary Information
Read a summary about a secure, online tool that healthcare professionals and support staff registered with Exact Sciences Laboratories can use to quickly and efficiently place orders, view order status, and get test results online.
Order a Cologuard Test Through EpicCare® LinkTM EMR Reference Guide
Read an in-depth explanation and guide on how to use a secure, online tool that healthcare professionals and support staff registered with Exact Sciences Laboratories can use to quickly and efficiently place orders, view order status, and get test results online.
Order a Cologuard Test by Fax
Fill out this order form entirely and fax it to Exact Sciences at 1-844-870-8875.
Order a Cologuard Test Through Your EMR
Quick start guide for ordering a Cologuard test through your EMR.
Coverage for a Follow-up Colonoscopy Summary Guide for Providers and Medical Offices
Information from the American Gastroenterological Association and Fight CRC about the 2023 requirement that Medicare, ACA, and commercial plans cover a colonoscopy following a positive stool-based test for CRC, including what this means for providers and how to code the change correctly.
Provider Status Report Enrollment Form Single Location
Sign up to receive biweekly fax updates about your Cologuard orders and a summary of your eligible patients due for rescreening from a single location.
Completion Tips/Provider Adherence Resource
This resource details some tips that may help eligible patients adhere to the CRC screening recommended for them.
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Patient outreach letters
After Visit Summary Letter
Send this letter to your patients after prescribing the Cologuard test to set expectations once they receive it.
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Patients Aged 45-49 Years Screening Letter
Complete and send this letter template to eligible patients aged 45-49 years. It describes how CRC affects this age group and how the Cologuard test may be an appropriate option.
Cologuard Rescreening Order Letter
Patient received a negative Cologuard result 3+ years ago (overdue) and HCP has ordered another Cologuard test for the patient.
Cologuard Rescreening Advance Order Letter
Patient received a negative Cologuard result less than 3 years ago (due soon) and HCP has ordered another Cologuard test for the patient. It will ship when they are eligible to be screened.
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GI Resources
Patient Cologuard Order Letter Template From GI
A letter template that GIs can share with eligible patients who may have missed or cancelled their last CRC screening colonoscopy.
Patient Cologuard Rescreen Letter Template From GI
A letter template that GIs can share with patients who are eligible for a rescreen.
Declined Colonoscopy Letter Template From GI
A letter template for GIs to share with HCPs when an eligible referred patient has declined a colonoscopy.
Cologuard Health System Letter Template From GI
A GI letter template that outlines the importance of CRC screening and can be shared with an HCP.
Unsuccessful Scheduling Attempt From GI
A letter template for GIs to share with HCPs when they have not been successful in scheduling an eligible patient’s testing procedure.
GI Alignment Letter Template
Gastroenterologists can use this letter to encourage primary care providers to help close the CRC screening gap by offering the Cologuard test to their average-risk patients as soon as they are eligible.
ACA=Affordable Care Act; CRC=colorectal cancer; EMR=electronic medical record; GI=gastrointestinal; HCP=healthcare provider.